Bilde av Hansen, Espen Holst
Bilde av Hansen, Espen Holst
The Norwegian College of Fishery Science espen.hansen@uit.no +4777649262 Tromsø You can find me here

Espen Holst Hansen


Job description

Professor i marin bioteknologi

Nestleder ved Norges fiskerihøgskole med ansvar for forskning

Medlem i fakultetsstyret ved BFE


  • Hosea, Yannik Karl Heinz, Ole Hinnerk, Espen Holst, Jeanette Hammer, Teppo :
    Biodiversity and Biological Interactions of Actinobacteria Associated with Deep Sea and Intertidal Marine Invertebrates
    Marine Drugs 17. octubre 2025 DOI
  • Sailesh, Johan Mattias, Krupová, Teppo, Kine Østnes, Jeanette Hammer et al.:
    Metabolomics-Guided Discovery of Bipolarolides H−O, New Ophiobolin-Type Sesterterpenes with Antibacterial Activity from the Marine-Derived Fungus Uzbekistanica storfjordensis sp. nov.
    Journal of natural products 2025 DOI / ARKIV
  • Sara Maria, Kine Østnes, Guillaume Axel, Espen Holst, Jeanette Hammer :
    Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
    Scientific Reports 2025 DOI / ARKIV
  • Laura, Kine Østnes, Johan Mattias, Jeanette Hammer, Espen Holst, Jörn et al.:
    Discovery of thiazostatin D/E using UPLC-HR-MS2-based metabolomics and σ-factor engineering of Actinoplanes sp. SE50/110
    Frontiers in Bioengineering and Biotechnology 2024 DOI / ARKIV
  • Jon Brage, Terje, Karley Lynn, Agnethe Hansen, Torbjørn Norberg, Lars et al.:
    Lipidome Plasticity Enables Unusual Photosynthetic Flexibility in Arctic vs. Temperate Diatoms
    Marine Drugs 2024 DOI / ARKIV
  • Yannik Karl Heinz, Anton, Johan Mattias, Oda Sofie Bye, Jeanette Hammer, Kine Østnes et al.:
    Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
    Frontiers in Microbiology 2023 DOI / ARKIV
  • Yannik Karl Heinz, Ole Christian, Chun, Espen Holst, Jeanette Hammer :
    Selective isolation of Arctic marine actinobacteria and a down-scaled fermentation and extraction strategy for identifying bioactive compounds
    Frontiers in Microbiology 21. octubre 2022 DOI / ARKIV
  • Giovanna, Mariana, Ana Varela, Adele, Lous G, Espen Holst et al.:
    Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications
    Marine Drugs 2022 DOI / ARKIV
  • Hans Christian, Gunilla, John-Steinar, Jo, Edel O., Karl-Erik et al.:
    Mass Cultivation of Microalgae: I. Experiences with Vertical Column Airlift Photobioreactors, Diatoms and CO2 Sequestration
    Applied Sciences 2022 DOI / ARKIV
  • Fazlin, Yannik Karl Heinz, Espen Holst, Jeanette Hammer, Johan Mattias, Tobias et al.:
    Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
    Marine Drugs 2022 DOI / ARKIV
  • Marte, Venke, Kumar, Johan, Teppo, Jeanette Hammer et al.:
    Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
    Molecules 2021 DOI / ARKIV
  • Marte, Philip, Eric, Jeanette Hammer, Espen, Johan et al.:
    Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
    Frontiers in Microbiology 2021 DOI / ARKIV
  • Kine Østnes, Ida Kristine Østnes, Céline Sarah Marine, Marte, Jeanette Hammer, Espen Holst :
    Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons
    Natural Product Communications 2021 DOI / ARKIV
  • Renate Døving, Jeanette Hammer, Hans Christian, Anne-Marie, Espen Holst :
    Bioactivity of a Marine Diatom (Porosira glacialis [Grunow] Jorgensen 1905) Cultivated With and Without Factory Smoke CO2
    Industrial Biotechnology 2021 DOI / ARKIV
  • Venke, Marte, Heba Raid, Johan, Espen, Teppo et al.:
    Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
    Molecules 2021 DOI / ARKIV
  • Yannik Karl-Heinz, Solveig, Jeanette Hammer, Espen :
    Qualitative and quantitative comparison of liquid–liquid phase extraction using ethyl acetate and liquid–solid phase extraction using poly-benzyl-resin for natural products
    Applied Sciences 2021 DOI / ARKIV
  • Ole Christian, Lingwei, Jeanette Hammer, Espen, Bjørn, Chun et al.:
    Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation
    IMA Fungus 2021 DOI / ARKIV
  • Hans Christian, Edel O., Ingeborg Hulda, Jon Brage, Lars, Ragnhild Aven et al.:
    Inclusion of photoautotrophic cultivated diatom biomass in salmon feed can deter lice
    PLOS ONE 29. julio 2021 DOI / ARKIV
  • Renate Døving, Richard Andre, Fredrika, Jeanette Hammer, Hans Christian, Espen Holst :
    Adding zooplankton to the OSMAC toolkit: Effect of grazing stress on the metabolic profile and bioactivity of a diatom
    Marine Drugs 2021 DOI / ARKIV
  • Chiara, Kirsti, Gennaro, Jeanette Hammer, Adrianna, Espen Holst :
    Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity
    Marine Drugs 17. marzo 2020 DOI / ARKIV
  • Jørgen A, Espen Holst, Tor Jacob :
    Effects of supplemental LED light quality and reduced growth temperature on swede (Brassica napus L. ssp. rapifera Metzg.) root vegetable development and contents of glucosinolates and sugars
    Journal of the Science of Food and Agriculture 2020 DOI / ARKIV
  • Yannik Karl-Heinz, Marte, Johan, Kine Østnes, Jeanette Hammer, Espen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. julio 2020 DOI / ARKIV
  • Raja Priyanka Mary Michael, Espen, Johan, Jeanette hammer, Kine Østnes :
    Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
    Natural Product Research 2019 DOI / ARKIV
  • Kine Østnes, Jeanette hammer, Annette, Sunil Kumar, Marianne, Kåre Bredeli et al.:
    Kinase chemodiversity from the Arctic: the breitfussins
    Journal of Medicinal Chemistry 2019 DOI / ARKIV
  • Yannik Karl-Heinz, Kine Østnes, Johan, Sara Maria, Espen, Jeanette Hammer :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 DOI / ARKIV
  • Sailesh, Espen Holst :
    Bioprospecting of driftwood-associated fungi from the Arctic: Mass spectrometry-based untargeted metabolomics approach for identification of bioactive secondary metabolites
    UiT Norges arktiske universitet 13. noviembre 2025
  • Anne, Espen Holst, Gunilla Kristina, Magnar :
    Et alternativ til elektrifisering av Melkøya finnes. Bærekraftig er det også.
    2025 ARKIV
  • Marit, Kristine, Agnethe Hansen, Jon Brage, Kine Østnes, Espen Holst et al.:
    LC-Orbitrap MS/MS based untargeted lipidomics of marine microalgae
    2023
  • Espen Holst :
    MARINE BIOPROSPECTING WITH AN ARCTIC PERSPECTIVE: THE MARBIO SCREENING PLATFORM AND ITS INVOLVEMENT IN LARGER EUROPEAN PROJECTS
    2023
  • Magnus Andersland, Kine Østnes, Espen Holst, Terje :
    Use of metabolomics to identify secondary metabolites from marine algae biomass
    2023
  • Espen Holst, Kine Østnes, Jeanette Hammer :
    HotBio - a Horizon Europe MSCA Doctoral Network in Marine Biodiscovery
    2023
  • Yannik Karl Heinz, Anton, Johan Mattias, Oda Sofie Bye, Jeanette Hammer, Kine Østnes et al.:
    Corrigendum: Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin (Frontiers in Microbiology, (2023), 14, (1130018), 10.3389/fmicb.2023.1130018)
    Frontiers in Microbiology 2023 DOI
  • Espen Holst :
    Discovery of new antibacterial compounds from the Arctic Ocean
    2023
  • Guillaume, Kine Østnes, Jeanette Hammer, Espen Holst, Annette, Bengt Erik et al.:
    A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
    2023
  • Espen Holst :
    Fra havets bunn til sykehuset
    2023 ARKIV
  • Yannik Karl Heinz, Jeanette Hammer, Espen Holst :
    Conference-presentation about bioactivity screening and the SuReMetS Project at the seminar for Enzymatic protein hydrolysis and Bioactive peptides
    2022
  • Yannik Karl Heinz, Jeanette Hammer, Espen Holst :
    Marine rest-rawmaterials for health – how to increase the value of by-products?
    2022
  • Espen Holst :
    Marbio - A platform for marine natural products drug discovery
    2021
  • Yannik Karl-Heinz, Njål, Espen Holst, Jeanette Hammer, Jascha, Wolfgang R. et al.:
    The SuReMetS-project - From sustainable resources to novel marine nutraceuticals for the management of metabolic syndrome
    2021
  • Yannik Karl Heinz, Jeanette Hammer, Espen Holst :
    Presentation at the Biotech-North and Cod-Cluster about the metabolic syndrome, SuReMetS project and screening of rest-raw material.
    2021
  • Anette, Birthe, Hans Christian, Sten Ivar, Bjørn-Steinar, Ragnhild Aven et al.:
    Mikroalger i fôr, ny løsning for å redusere lusepåslag på laks – Faglig sluttrapport
    Nofima 2020 ARKIV
  • Espen Holst, Kine Østnes, Jeanette hammer :
    Nye legemidler fra havet?
    04. enero 2020 FULLTEKST
  • Espen Holst, Jeanette hammer :
    Molekylet som kan stoppe brystkreft
    07. enero 2020
  • Espen :
    Use of ion mobility in mass spectrometry-based metabolomics of marine natural products
    2019
  • Marte, Jeanette Hammer, Teppo, Espen Holst, Kine Østnes, Chun :
    Biodiscovery of Antimicrobial Compounds from Arctic Marine Microorganisms
    2019
  • Espen :
    Marine bioprospecting - The search for bioactive compounds of scientific and commercial interest in the marine environment
    2019
  • Renate Døving, Espen, Hans Christian, Anne-Marie :
    Extract of a marine diatom negatively affects development in sea urchin (Paracentrotus lividus) embryos
    2019
  • Yannik Karl-Heinz, Espen :
    Quantitative comparison of solid and liquid phase extraction of natural products from bacterial fermentations
    2019
  • Priyanka, Espen, Johan, Jeanette hammer, Kine Østnes :
    Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
    2019
  • Marte, Teppo, Kine Ø., Venke, Espen, Jeanette hammer :
    Exploring the chemical and biological potential of Arctic marine fungi
    2019

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    Research interests

    Mitt ansvarsområde i Marbio er kjemisk karakterisering av bioaktive naturstoffer fra arktiske planter, dyr og mikroorganismer. Jeg jobber hovedsaklig med følgende teknikker:

    • Massespektrometri (MS)
    • Kromatografi

    Teaching

    BIO-2606 Generell og marin bioteknologi




    Forskningsparken 1 A206


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