Bilde av Kondratyev, Timofey
Bilde av Kondratyev, Timofey
Department of Medical Biology timofey.kondratiev@uit.no +4777644780 95215728 Tromsø You can find me here

Timofey Kondratyev


Job description

Arbeid med eksperimentelle dyremodeller, statisisk dataanalyse (SigmaPlot), 3D modellering (Autodesk Fusion 360), 3D printing, laboratoriearbeid, laboratoriedrift og vedlikehold, oppdatering av stoffkartoteket CHESS, kjemikalier og farlig avfall håndtering ved Kardiovaskulær forskningsgruppe, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet.


  • Adrina, Anders Lund, Markus, Natalia, Timofey, Ole Martin et al.:
    Moderate but not severe hypothermia increases intracellular cyclic AMP through preserved production and reduced elimination
    Cryobiology 2023 DOI / ARKIV
  • Ole Magnus, Timofey, Gary C., Torkjel :
    Functional recovery after accidental deep hypothermic cardiac arrest: Comparison of different cardiopulmonary bypass rewarming strategies
    Frontiers in Physiology 2022 DOI / ARKIV
  • Ole Magnus, Stig Eggen, Timofey, Gary C., Torkjel :
    Cooling to hypothermic circulatory arrest by immersion vs. cardiopulmonary bypass (CPB): Worse outcome after rewarming in immersion cooled pigs
    Frontiers in Physiology 31. marzo 2022 DOI / ARKIV
  • Torstein Lindahl, Ole Magnus, Bjarne, Timofey, Gary C., Torkjel :
    Enhanced Blood Clotting After Rewarming From Experimental Hypothermia in an Intact Porcine Model
    Frontiers in Physiology 2022 DOI / ARKIV
  • Sergei, Jan Harald, Rizwan, Torstein Lindahl, Timofey, Gary C. et al.:
    Autoregulation of Cerebral Blood Flow During 3-h Continuous Cardiopulmonary Resuscitation at 27°C
    Frontiers in Physiology 2022 DOI / ARKIV
  • Anders Lund, Adrina, Natalia, Timofey, Ole Martin, Georg et al.:
    Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia
    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2022 DOI / ARKIV
  • Adrina, Anders Lund, Natalia, Timofey, Ole Martin, Roy Andre et al.:
    Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate
    Frontiers in Physiology 2022 DOI / ARKIV
  • Erik Sveberg, Anders Lund, Timofey, Karen, Godfrey L, Torkjel :
    Resistance to ventricular fibrillation predicted by the QRS/QTc - ratio in an intact rat model of hypothermia/rewarming
    Cryobiology 2021 DOI / ARKIV
  • Joar O., Rizwan, Torstein, Jan Harald, Sergey, Timofey et al.:
    Rewarming With Closed Thoracic Lavage Following 3-h CPR at 27°C Failed to Reestablish a Perfusing Rhythm
    Frontiers in Physiology 2021 DOI / ARKIV
  • Rizwan, Erik Sveberg, Predip, Timofey, Marie, Gary C. et al.:
    Cardiovascular Effects of Epinephrine During Experimental Hypothermia (32°C) With Spontaneous Circulation in an Intact Porcine Model
    Frontiers in Physiology 2021 DOI / ARKIV
  • Anders Lund, Adrina Kalasho, Natalia, Timofey, Ole Martin, Roy Andre et al.:
    Treatment of cardiovascular dysfunction with PDE5-inhibitors - temperature dependent effects on transport and metabolism of cAMP and cGMP
    Frontiers in Physiology 2021 DOI / ARKIV
  • Jan Harald, Torstein, Timofey, Olav, Gary C., Torkjel :
    Maintaining intravenous volume mitigates hypothermia-induced myocardial dysfunction and accumulation of intracellular Ca2+
    Experimental Physiology 2021 DOI / ARKIV
  • Jan Harald, Torstein Lindahl, Sergey, Rizwan, Brage, Timofey et al.:
    Effects of rewarming with extracorporeal membrane oxygenation to restore oxygen transport and organ blood flow after hypothermic cardiac arrest in a porcine model
    Scientific Reports 23. septiembre 2021 DOI / ARKIV
  • Svein E., Timofey, Ingrid, Torkjel :
    Effects of Cold Decompression on Hemodynamic Function and Decompression Sickness Risk in a Dry Diving Rat Model
    Frontiers in Physiology 2021 DOI / ARKIV
  • Brage, Timofey, Erik Sveberg, Torkjel :
    Comparison between two pharmacologic strategies to alleviate rewarming shock: vasodilation vs. inodilation
    Frontiers in Medicine 2020 DOI / ARKIV
  • Jan Harald, Sergey, Rizwan, Torstein Lindahl, Timofey, Torvind et al.:
    Study of the effects of 3 h of continuous cardiopulmonary resuscitation at 27°C on global oxygen transport and organ blood flow
    Frontiers in Physiology 2020 DOI / ARKIV
  • Svein Erik, Timofey, Ingrid, Torkjel :
    Continuous Hemodynamic Monitoring in an Intact Rat Model of Simulated Diving
    Frontiers in Physiology 13. enero 2020 DOI / ARKIV
  • Vladimir, Nurlan, Timofey, Aidos, Abay K., Maya et al.:
    The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest
    BMC Anesthesiology 2019 DOI / ARKIV
  • Torstein Lindahl, Timofey, Torkjel :
    Extracorporeal rewarming from experimental hypothermia: Effects of hydroxyethyl starch versus saline priming on fluid balance and blood flow distribution
    Experimental Physiology 2019 DOI / ARKIV
  • Sergey, Rizwan, Jan Harald, Torstein Lindahl, Timofey, Gary C. et al.:
    Organ blood flow and O2 transport during hypothermia (27°C) and rewarming in a pig model
    Experimental Physiology 29. octubre 2018 DOI / FULLTEKST
  • Erik Sveberg, Brage, Timofey, Erik R., Torkjel :
    Effects of hypothermia and rewarming on cardiovascular autonomic control in vivo
    Journal of applied physiology 2018 DOI
  • Brage, Timofey, Erik Sveberg, Torkjel :
    The beneficial hemodynamic effects of afterload reduction by sodium nitroprusside during rewarming from experimental hypothermia
    Cryobiology 2017 DOI
  • Kathrine, Timofey, Torkjel, Lars J. :
    Effects of Constant Flow vs. Constant Pressure Perfusion on Fluid Filtration in Severe Hypothermic Isolated Blood-Perfused Rat Lungs
    Frontiers in Medicine 2016 DOI / ARKIV
  • Erik Sveberg, Torstein, Timofey, Svein Erik, Georg, Torkjel :
    Negative inotropic effects of epinephrine in the presence of increased β-adrenoceptor sensitivity during hypothermia in a rat model
    Cryobiology 2015 DOI
  • Erik Sveberg, Brage, Timofey, Gary C., Torkjel :
    Cardiovascular effects of levosimendan during rewarming from hypothermia in rat
    Cryobiology 30. septiembre 2014 DOI
  • Erik Sveberg, Timofey, Torkjel :
    Milrinone ameliorates cardiac mechanical dysfunction after hypothermia in an intact rat model
    Cryobiology 2014 DOI
  • Ragnhild Margrete, Timofey, Torkjel :
    Myocardial calcium overload during graded hypothermia and after rewarming in an in vivo rat model
    Acta Physiologica 2013 DOI
  • Ole Magnus, Ole-Jakob, Timofey, Tor Magne, Georg, Torkjel :
    Changes in cardiovascular effects of dopamine in response to graded hypothermia in vivo
    Critical Care Medicine 2012 DOI
  • Evgeny, Alexey Anatolievich, Timofey, Andrey Yurjevich, Vsevolod, Mikhail et al.:
    Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy
    BMC Anesthesiology 2012 DOI / ARKIV
  • Ole Magnus, Ole-Jakob, Timofei, Tor Magne, Torkjel :
    Post-hypothermic cardiac left ventricular systolic dysfunction after rewarming in an intact pig model
    Critical Care 2010 DOI / FULLTEKST
  • Assami, Ole-Jakob, Erling Johan, Thor Allan, Thomas Vennø, Timofei et al.:
    High Resolution Speckle Tracking Dobutamine Stress Echocardiography Reveals Heterogeneous Responses in Different Myocardial Layers: Implication for Viability Assessments
    Journal of the American Society of Echocardiography 2010 DOI
  • Timofei, Ragnhild Margrete, Ellen, Torkjel :
    Myocardial mechanical dysfunction and calcium overload following rewarming from experimental hypothermia in vivo
    Cryobiology 2008 DOI
  • ys, Torkjel, Timofei, y s, GC :
    changes in cardiovascular beta-adrenoceptor responses during hypothermia
    Cryobiology 2008
  • Timofei, Torkjel :
    Effects of sympathetic stimulation during cooling on hypothermic as well as posthypothermic hemodynamic function
    Canadian Journal of Physiology and Pharmacology 2006 DOI
  • Elena, Mikhail, Timofei, Jan Ole, Torkjel, Bjarne :
    Induction of monocytic TF expression after rewarming from hypothermia in vivo is counteracted by heat shock in c-Jun-dependent manner
    Arteriosclerosis, Thrombosis and Vascular Biology 2006
  • Timofei, Kristina, Eivind S. P., Mikhail, Torkjel :
    Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?
    American Journal of Physiology. Heart and Circulatory Physiology 2006
  • Timofei, Eivind S.P., Øystein Thunheim, Tor-Bjarne, Torkjel :
    Cardiovascular effects of epinephrine during rewarming from hypothermia in an intact animal model
    Journal of applied physiology 2006 DOI
  • Anders Lund, Adrina, Natalia Nikolaevna, Timofey, Ole Martin, Georg et al.:
    Correction to: Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia (Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, (2022), 30, 1, (73), 10.1186/s13049-022-01060-y)
    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2024 DOI
  • Vladimir, Timofey, Maya, Nurlan, Mikhail, Aidos et al.:
    Effects of morphine or ketamine in rats with asphyxial cardiac arrest: a pilot study
    2017 ARKIV
  • Vladimir, Timofey, Maya, Nurlan, MA, Aidos et al.:
    EFFECTS OF MORPHINE OR KETAMINE IN RATS WITH ASPHYXIAL CARDIAC ARREST: THE RESULTS OF PILOT STUDY
    2017
  • Ole-Jakob, Torvind, Jens Petter, Timofey, Espen W., Truls :
    Elevated preload is critical for synchronization of myocardial lengthening (e) and mitral inflow (E) in acute ischemic acute heart failure
    The FASEB Journal 2013
  • Svein Erik, Timofei, Andreas, Ulrik, Alf O, Torkjel :
    Dynamic changes in cardiovascular function during diving and decompression at different core temperatures
    2010
  • Ole magnus, Ole-Jakob, Timofei, Tor Magne, Torkjel :
    CARDIAC FUNCTION DURING SEVERE IMMERSION HYPOTHERMIA AND REWARMING IN PIGS
    Intensive Care Medicine 2010
  • OM, Ole-Jakob, Timofei, Tor Magne, Georg, Torkjel :
    DOPAMINE INFUSIONS IN NORMOTHERMIA, SEVERE HYPOTHERMIA AND DURING REWARMING: PHARMACOKINETICS AND CARDIOVASCULAR FUNCTION IN A PIG MODEL OF SURFACE COOLING AND REWARMING
    Intensive Care Medicine 2010
  • Erik Sveberg, Timofei, Torkjel :
    Cardiovascular effects of milrinone during rewarming from hypothermia in an intact animal model
    2009
  • YS, Torkjel, Timofei, YS, GC :
    The physiologic response to isoproterenol during hypothermia and rewarming
    The FASEB Journal 2007
  • YS, Torkjel, Timofei, GC :
    Change in physiologic response to isoproterenol induced by hypothermia is not reversed by rewarming
    Acta Anaesthesiologica Scandinavica 2007
  • elena, Mikhail, Timofei, Jan Ole, torkjel, Bjarne :
    Heat shock prevents tissue factor expression after rewarming from lethal hypothermia in c-Jun-dependent manner
    2006
  • elena, Mikhail, Timofei, Jan Ole, torkjel, Bjarne :
    Heat Shock Prevents Tissue Factor Induction after Rewarming from Lethal Hypothermia in a c-Jun-Dependent Manner
    2006
  • Timofei, torkjel :
    Hypothermia-induced myocardial dysfunction. An in vivo experimental study with special reference to effects of epinephrine applied for posthypothermic cardiovascular resuscitation
    UiT Norges arktiske universitet 2006

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    Research interests

    Aksidentell hypotermi


    Member of research group




    MH øst L7.243


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