Bilde av Brækkan, Sigrid Kufaas
Bilde av Brækkan, Sigrid Kufaas
Department of Clinical Medicine sigrid.brakkan@uit.no +4777625106 +47 957 47627 Tromsø

Sigrid Kufaas Brækkan


Job description

Professor, Tromboseforskning (TREC)

 


  • Carl Arne Løchen Arnesen, Kristian Hveem, Maiken Elvestad Gabrielsen, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Body height and risk of venous thromboembolism in men vs women
    Journal of Thrombosis and Haemostasis 2025 DOI
  • Christopher Antoun, Julia Oto, Vania Maris Morelli, Kristian Hveem, Sigrid Kufaas Brækkan, Pilar Medina et al.:
    Plasma miR-145-5p Levels and Risk of Future Cancer—Results from the HUNT Study
    International Journal of Molecular Sciences 2025 DOI
  • Erin Mathiesen Hald, Maja-Lisa Løchen, Ellisiv B. Mathiesen, Kristian Hveem, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    Joint effects of atrial fibrillation and prothrombotic genotypes on the risk of ischemic stroke
    Journal of Thrombosis and Haemostasis 2025 DOI
  • Christabel Esi Damoah, Solveig Marie Valderhaug, Omri Snir, Kristian Dalsbø Hindberg, Sigrid Kufaas Brækkan, Steven P. Grover et al.:
    Elevated Plasma MBL Levels Are Associated With Risk of Future Venous Thromboembolism: HUNT
    Arteriosclerosis, Thrombosis and Vascular Biology 2025 DOI
  • Oda Leknessund, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Resting Heart Rate and Risk of Incident Venous Thromboembolism: The Tromso Study
    Thrombosis and Haemostasis 2025 DOI
  • Nikolai Hagensen Eide, Camilla Langholm, Fridtjof Balteskard Rinde, Nick van Es, Kristian Hveem, Sigrid Kufaas Brækkan et al.:
    Mortality risk after cancer-related venous thromboembolism has decreased over the last three decades: the HUNT and Tromsø studies
    Haematologica 2025 DOI
  • Birgitte Gladsø Tøndel, Joakim Knutsen Sejrup, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen et al.:
    Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 ARKIV / DOI
  • Luuk J.J. Scheres, Sigrid Kufaas Brækkan, Judith P.L. Verlaan, Suzanne C. Cannegieter, John Bjarne Hansen, Vania Maris Morelli :
    The fatty liver index and risk of incident venous thromboembolism: the Tromsø Study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 ARKIV / DOI
  • Carl-Arne Arnesen, Line Holtet Evensen, Kristian Hveem, Maiken Elvestad Gabrielsen, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 ARKIV / DOI
  • Vania Maris Morelli, Omri Snir, Kristian Dalsbø Hindberg, Kristian Hveem, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    High microRNA-145 plasma levels are associated with decreased risk of future incident venous thromboembolism: the HUNT study
    Blood 2024 ARKIV / DOI
  • Zygimantas Zaboras, Camilla Tøvik Jørgensen, Andreas Stensvold, Heidi Hassel Pettersen, Aleksandra Grdinic Galovic, Sigrid Kufaas Brækkan et al.:
    Real-world Data on Treatment Patterns and Bleeding in Cancer-associated Thrombosis: Data from the TROLL Registry
    TH Open 2024 ARKIV / DOI
  • Sigrid Kufaas Brækkan, Asbjørn Lund Onsaker, Therese Haugdahl Nøst, Weihong Tang, Kristian Dalsbø Hindberg, Vania Maris Morelli et al.:
    The Plasma Proteome and Risk of Future Venous Thromboembolism—Results from the HUNT Study
    Thrombosis and Haemostasis 2024 ARKIV / DOI
  • Christopher Antoun, Vårin Eiriksdatter Wikan, Øyvind Øverli, Thor Ueland, Gholamreza Jafari Yeganeh, Sigrid Kufaas Brækkan et al.:
    Plasma microRNA-145-5p as a diagnostic biomarker for acute deep vein thrombosis
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Camilla Tøvik Jørgensen, Sigrid Kufaas Brækkan, Eli Førsund, Heidi Hassel Pettersen, Eirik Tjønnfjord, Waleed Ghanima et al.:
    Incidence of venous thromboembolism, recurrence, and bleeding after isolated superficial vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Steven P. Grover, Tomohiro Kawano, Jun Wan, Pansakorn Tanratana, Zsofia Polai, Young J. Shim et al.:
    C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
    Blood 2023 ARKIV / DOI
  • Steven P. Grover, Omri Snir, Kristian Dalsbø Hindberg, Tatianna M. Englebert, Sigrid Kufaas Brækkan, Vania Maris Morelli et al.:
    High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Sigrid Kufaas Brækkan, John Bjarne Hansen :
    VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology
    Thrombosis Update 2023 ARKIV / DOI
  • Magnus Edvardsen, Ellen-Sofie Hansen, Thor Ueland, Pål Aukrust, Sigrid Kufaas Brækkan, Vania Maris Morelli et al.:
    Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Monique J.T. Crobach, Rayna J.S. Anijs, Sigrid Kufaas Brækkan, Marianne T. Severinsen, Jens Hammerstrøm, Hanne Skille et al.:
    Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
    Blood Advances 2023 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan et al.:
    Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Samantha Swamy, Thor Ueland, John Bjarne Hansen, Omri Snir, Sigrid Kufaas Brækkan :
    Plasma levels of P-selectin and future risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Fridtjof Balteskard Rinde, Camilla Tøvik Jørgensen, Heidi Hassel Pettersen, John Bjarne Hansen, Waleed Ghanima, Sigrid Kufaas Brækkan :
    Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Espen Waage Skjeflo, Line Holtet Evensen, Søren Beck Jensen, Nadezhda Latysheva, Annika Elisabet Michelsen, Thor Ueland et al.:
    Complement factors B, D, C3bBbP and risk of future venous thromboembolism
    Clinical Immunology 2023 ARKIV / DOI
  • loannis T. Farmakis, Stefano Barco, Lukas Hobohm, Sigrid Kufaas Brækkan, Jean M. Connors, George Giannakoulas et al.:
    Maternal mortality related to pulmonary embolism in the United States, 2003–2020
    American Journal of Obstetrics & Gynecology MFM (AJOG MFM) 2023 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength in venous thromboembolism: risk of recurrence and mortality
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2023 ARKIV / DOI
  • Camilla Tøvik Jørgensen, Mazdak Tavoly, Elise Førsund, Heidi Hassel Pettersen, Eirik Tjønnfjord, Waleed Ghanima et al.:
    Incidence of bleeding and recurrence in isolated distal deep vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Maria A. De Winter, Harry R. Büller, Marc Carrier, Alexander T. Cohen, John Bjarne Hansen, Karin A. H. Kaasjager et al.:
    Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
    European Heart Journal 2023 ARKIV / DOI
  • Dana Meknas, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Surgery As a Trigger for Incident Venous Thromboembolism: Results from a Population-Based Case-Crossover Study
    TH Open 2023 ARKIV / DOI
  • Vårin Eiriksdatter Wikan, Birgitte Gladsø Tøndel, Vania Maris Morelli, Ellen Elisabeth Brodin, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review
    Diagnostics (Basel) 2023 ARKIV / DOI
  • Tobias Frischmuth, Birgitte Gladsø Tøndel, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    The Risk of Incident Venous Thromboembolism Attributed to Overweight and Obesity: The Tromso Study
    Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Lisa Jakobsen, Tobias Frischmuth, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Line Holtet Evensen, Carl-Arne Arnesen, Frits Richard Rosendaal, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hveem et al.:
    The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Camilla Tøvik Jørgensen, Mazdak Tavoly, Heidi Hassel Pettersen, Eli Førsund, Christina Roaldsnes, Magnus Kringstad Olsen et al.:
    The venous thrombosis registry in Østfold Hospital (TROLL registry) - design and cohort description
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Christabel Esi Damoah, Omri Snir, Kristian Dalsbø Hindberg, Peter Garred, Judith K Ludviksen, Sigrid Kufaas Brækkan et al.:
    High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
    Arteriosclerosis, Thrombosis and Vascular Biology 2022 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, Bjørn Heine Strand, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 FULLTEKST / ARKIV / DOI
  • Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, Daniel C. Posner et al.:
    Stroke genetics informs drug discovery and risk prediction across ancestries
    Nature 2022 ARKIV / DOI
  • Florian Thibord, Derek Klarin, Jennifer A. Brody, Ming-Huei Chen, Michael G. Levin, Daniel I. Chasman et al.:
    Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
    Circulation 2022 ARKIV / DOI
  • Birgitte Gladsø Tøndel, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
    Journal of Thrombosis and Haemostasis 11. julio 2022 ARKIV / DOI
  • Joakim Knutsen Sejrup, Birgitte Gladsø Tøndel, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen et al.:
    Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Elias Allarai, Wei-Hsuan Lee, Stephen Burgess, Susanna C. Larsson, Sara Lindstrom, Lu Wang et al.:
    Genetically predicted cortisol levels and risk of venous thromboembolism
    PLOS ONE 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Venous thromboembolism and risk of depression: a population-based cohort study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Omri Snir, line Wilsgård, Nadezhda Latysheva, Casper Ullsten-Wahlund, Sigrid Kufaas Brækkan, Kristian Dalsbø Hindberg et al.:
    Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
    Clinical Epidemiology 2022 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Pål Aukrust, Thor Ueland, Sigrid Kufaas Brækkan, John Bjarne Hansen et al.:
    Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan et al.:
    Galectin-3-binding protein and future venous thromboembolism
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Oda Leknessund, Vania Maris Morelli, Bjørn Heine Strand, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Corrigendum to ‘Hand grip strength and risk of incident venous thromboembolism: The Tromsø study’: [Res Pract Thromb Haemost. 2022 Nov 4;6/7 e12833] (Research and Practice in Thrombosis and Haemostasis (2022) 6(7), (S2475037922024669), (10.1002/rth2.12833))
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Steven P. Grover, Linda Sundler Björkman, Sigrid Kufaas Brækkan, Bengt Zöller, John Bjarne Hansen, Nigel Mackman :
    “C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study”: comment from Grover et al
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Steven P. Grover, Sigrid Kufaas Brækkan, Nigel Mackman, John Bjarne Hansen :
    “High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: reply
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Sigrid Kufaas Brækkan :
    NRK reportasje blodproppforskning
    06. abril 2021

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    CV

    Utdanning/Grad

    2010       PhD i Helsefag, Universitetet i Tromsø

    2005       Master i Farmasi, Universitetet i Tromsø

      

    Tidligere akademiske stillinger

    2012-13  Postdoktor, Dep. of Clinical Epidemiology, Leiden University Medical Center, Nederland   

    2010-12  Postdoktor, Hematologisk forskningsgruppe, Universitetet i Tromsø (Helse-Nord midler)

    2008-09  Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT

    2006-08  PhD-student, Center for Atherothrombotic Research in Tromsø, UiT 

    2005-06  Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT

     

    Publikasjoner

    >185 fagfellevurderte originalartikler indeksert i PubMed. Har bidratt til mer enn 200 abstracts presentert og publisert i forbindelse med internasjonale vitenskapelige kongresser.

     

    Andre relevante vitenskapelige verv

    2021-2024: Associate Editor i Journal of Thrombosis and Haemostasis (JTH)

    2016-dd: Metodologisk reviewer for Journal of Thrombosis and Haemostasis (JTH)

    2016-2018: Medlem av junior advisory board for European Congress on Thrombosis and Haemostasis (ECTH)

     

    Priser og utmerkelser

    Young Investigator Award ISTH2016 (International Society of Thrombosis and Haemostasis)

    Det Helsevitenskapelige Fakultets pris til yngre forsker 2017

     

     Veiledning av PhD-studenter

    Fullførte doktorgrader: Hovedveileder: 5; Biveileder: 23

    Pågående doktorgrader: Hovedveileder for 5 og biveileder for 5