Angel Salvador Moldes-Anaya
Job description
Fagansvarlig syklotron og radiokjemi
Syklotron og radiokjemi enhet
PET-senteret, UNN
Work areas
Isotoper / Kromatografi / MikroCT-skanning / MikroPET-skanning / Radioaktivitet / Strålevern / Undervisning
Linn Samira Mari,
Clizia,
Imin,
Dawid,
Angel,
Andrzej J.
et al.:
Identification of Orthosteric GABAACS Omega 2025 DOI
Ursula,
Thomas Kolle,
Kristina Søborg,
Mathias,
Rune,
Angel
et al.:
Production of 67Cu at a biomedical cyclotron via 70Zn(p,α)67Cu reaction and its evaluation in a preclinical study using small animal SPECT/CT
Applied Radiation and Isotopes 2025 DOI
Piyapan,
Sukanya,
Chanisa,
Angel,
Rune,
Rodrigo
et al.:
Radiosynthesis and preclinical evaluation of a 68Ga-labeled tetrahydroisoquinoline-based ligand for PET imaging of C-X-C chemokine receptor type 4 in an animal model of glioblastoma
Marcel,
Ana,
Montserrat,
Yngve,
Angel,
Rodrigo
et al.:
Glioblastoma PET/MRI: kinetic investigation of [18F]rhPSMA-7.3, [18F]FET and [18F]fluciclovine in an orthotopic mouse model of cancer
Ahmet Oguzhan,
Mousumi,
Yu-Hsin,
Evelyn,
Lorenzo,
Angel
et al.:
Anxiolytic-like Effects of the Positive GABA-B Receptor Modulator GS39783 Correlate with Mice's Individual Basal Anxiety and Stress Reactivity
Hanne Friis,
Angel,
Cesilie Granum,
Lorenzo,
Trude M,
Rønnaug
et al.:
Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons
Richard,
Angel,
Terje,
Ana,
Maria Montserrat,
Ole Kristian
et al.:
Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH‐receptor ligands for brain SPECT imaging
Hanne Friis,
Cesilie Granum,
Rønnaug,
Trude,
Angel,
Judit
et al.:
PFOS-induced excitotoxicity is dependent on Ca2+ influx via NMDA receptors in rat cerebellar granule neurons
Angel,
Thomas,
Silvio,
Hilde Irene,
Terje,
Hans Christian
et al.:
Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ
Hanne Friis,
Inger Lise,
Mattis B,
Frode,
S. Ivar,
Angel
:
The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations
Christiane Kruse,
Angel
:
Biotransformation of the fungal neurotoxin Thomitrem A by primary rat hepatocytes
Toxicon 2016 DOI
H F,
Mattis Brænne,
Inger Lise,
Frode,
S. Ivar,
Angel
:
Mechanisms of penitrem-induced cerebellar granule neuron death in vitro: Possible involvement of GABA(A) receptors and oxidative processes
Neurotoxicology 2013 DOI
Gunnar Sundstøl,
Angel,
Christiane Kruse
:
Penitrem A and analogues: toxicokinetics, toxicodynamics including mechanism of action and clinical significance
World Mycotoxin Journal 09. agosto 2013 DOI
Angel,
Thomas,
Christiane Kruse,
Gunnar Sundstøl,
Aksel
:
Neurotoxicity of Penicillium crustosum secondary metabolites: Tremorgenic activity of orally administered penitrem A and thomitrem A and E in mice
Toxicon 2012 DOI
Angel S.,
Frode,
Gunnar Sundstøl,
Thomas,
S. Ivar,
Mattis Brænne
:
In vitro neuropharmacological evaluation of penitrem-induced tremorgenic syndromes: importance of the GABAergic system
Neurochemistry International 2011 DOI
Angel,
Thomas,
Silvio,
Frode,
Alistair Lawrence
:
Isolation and structure elucidation of secopenitrem D, an indole alkaloid from Penicillium crustosum Thom
Toxicon 2011 DOI
Gunnar Sundstøl,
Karin Hultin,
Angel,
Jurgen,
Aksel,
Gry
et al.:
Poisoning of dogs with tremorgenic Penicillium toxins
Medical Mycology 2010 DOI
Aksel,
Angel,
T,
Ida
:
Mykotoksinet penitrem A gir hjerneskader hos hunder
Norsk veterinærtidsskrift 2010
Angel S,
Tone Normann,
Gunnar Sundstøl,
Ida,
Thomas
:
Determination of cyclopiazonic acid in food and feeds by liquid chromatography-tandem mass spectrometry
Journal of Chromatography A 2009 DOI
Turid,
Kristin,
Sindhu,
Yngve,
Rodrigo,
Vera
et al.:
Preclinical assessment of [18F]AIF-FAPI for PET-imaging of cancer-associated fibroblast responses to radiotherapy
2025
Turid,
Kristin,
Sindhu,
Yngve,
Rodrigo,
Vera
et al.:
Preclinical evaluation of [18F]AIF-FAPI-74 PET-imaging as biomarker for monitoring cancer-associated fibroblast responses to radiotherapy
2025
Turid,
Kristin,
Sindhu,
Yngve,
Rodrigo,
Vera
et al.:
Exploring the effects of radiotherapy on cancer-associated fibroblasts by non-invasive PET-imaging
2025
Karoline,
Hanna,
Mathias,
Angel,
Jørn H
:
Towards a Novel Radiotracer for PET – Imaging of Glioblastoma
Targeting the Notch Signaling Pathway
2023
Michel Herranz,
Angel,
Bengt Erik,
Turid,
Inigo Zubiavrre
:
Innovative molecular imaging technique for Granzyme-B characterization as an emerging biomarker for radio-immunotherapy combinations
2022
Karoline,
Hanna,
Angel,
Jørn H,
Mathias
:
Towards a novel radiotracer for PET – imaging of glioblastoma
targeting the Notch signaling pathway
2022
Yngve,
Angel,
Richard,
Ana,
Montserrat,
Marcel
et al.:
Development of a carbon-11 labeled thienopyrimidine based radioligand for EGFR-tyrosine-kinase-inhibitor (TKI) specific PET imaging of glioblastoma
Journal of Nuclear Medicine 2021
Yngve,
Mathias,
Richard,
Montserrat,
Ana,
Julia
et al.:
SP-015 - Preliminary evaluation of a novel carbon-11 labeled brain-penetrant EGFR-TKI radiotracer for brain cancer imaging
Nuclear Medicine and Biology 2021 DOI
Richard,
Ana,
armas maria montserrat,
Jørn H,
Angel,
Terje
et al.:
Development and evaluation of gonadotropin releasing hormone SPECT radioligands
2018
Angel,
Lorenzo,
Samuel,
Daniel,
Jürgen,
Vegard
et al.:
Targetting mnemonic pathways of stress by cerebral perfusion using 99mTc-HMPAO SPECT/CT
2017
Kamilla Gjerland,
Angel,
Anniken,
Andreas,
Kirsten Brun,
Vegard
:
Intrahippocampal growth hormone modulates spatial memory
2017
Richard,
Jørn H,
Angel,
armas maria montserrat,
Ana,
Patrick
et al.:
Development and evaluation of gonadotropin releasing hormone (GnRH) SPECT radioligands
2017
Lorenzo,
Angel,
Vegard,
Kirsten Brun
:
Contextual fear encoded by hippocampal single units
2016
Kamilla Gjerland,
Angel,
Kirsten Brun,
Vegard
:
Intrahippocampal growth hormone modulates spatial memory
2016
Thomas,
Angel,
Jørn Eivind,
Anders,
Steinar M,
Ingebrigt
et al.:
Anti-diabetic activity from marine lipids: new anti-diabetic drugs
2016
Kamilla Gjerland,
Angel,
Kirsten Brun,
Vegard
:
The role of intrahippocampal growth hormone in spatial memory
2015
Angel,
Samuel,
Daniel,
Jürgen,
Vegard,
Kirsten Brun
:
Targeting mnemonic pathways of stress by cerebral perfusion using 99mTc-HMPAO SPECT/CT
2015
Thomas,
Angel,
Jørn Eivind,
Anders,
Steinar Martin,
Ingebrigt
et al.:
Anti-diabetic activity from marine lipids: new anti-diabetic drugs
2015
KG,
Angel,
Kirsten Brun,
Vegard
:
The role of intrahippocampal Growth hormone in spatial memmory
2015
Thomas,
Angel,
Laila,
Terje,
Steinar M,
Hilde Irene
:
Two near identical oxylipins from the diatom Chaetoceros karianus show isoform-specific agonist activity towards human peroxisome proliferator-activated receptors (PPARs)
2014
Angel,
Thomas,
Laila Norrheim,
Terje,
Hilde Irene,
Steinar
:
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae
2013
Angel,
Thomas,
Laila,
Hilde Irene,
Terje,
Steinar
:
Identifying natural products with agonist or modulatory activity against human nuclear receptors in extracts from cultured marine microalgae
2013
Thomas,
Angel,
Laila Norrheim,
Terje,
Steinar,
Hilde Irene
:
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae
2013
Thomas,
Angel,
Laila,
Terje,
Steinar M,
Hilde Irene
:
Identifying natural products with agonist activity against human nuclear receptors in extracts of cultured marine microalgae
2013
Angel
:
Toxicokinetics and toxicodinamics of penitrem A, a fungal neuroactive compound causing neurological disease in humans and animals
2012
Angel
:
Neurological disorders caused by fungal toxins: the case of penitrem-induced neuromycotoxicosis in dogs
2012
Angel S.
:
Undervurdert muggsoppgift
Forskning.no 2012
Gunnar Sundstøl,
Thomas,
Mattis Brænne,
Frode,
Aksel,
Angel
:
Poisoning by penicillium toxins-Clinical and brain receptor effects
Toxicology Letters 2012 DOI
Angel
:
Hunden kan dø av muggsopp i matavfall
Forskning.no 2012
Angel S.
:
Penitrem-induced neurological disease in Norway : clinical cases in dogs. Neuropharmacology and toxicokinetics of penitrem A. Structural elucidation of a novel penitremanalogue
Unipub forlag 2011
Angel S.,
Frode,
Gunnar Sundstøl,
Thomas,
S. Ivar,
Mattis Brænne
:
Hepatic metabolism and neuropharmacological evaluation of fungal tremorgenic syndromes: implication of the GABAergic and glutamatergic systems
2009
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Research interests
Radio- og kjernekjemi (Bruk av spesifikke radiomerkede molekyler for medisinsl avbildning ved hjelp av PET og SPECT hybrid teknikker, hovedinteresse hjerne avbildning)
C-11 og F-18 Radiokjemi
Radiometaler
Nevrofarmakologi og nevrotoksikologi
Neuroimaging (SPECT/PET/CT and PET/MR)
Teaching
Kursansvarlig Radiokjemi og kjernekjemi:
KJE-3316 Radiopharmaceutical Chemistry (10 ETCS, tilbys ved Institutt for kjemi, Mastergrad)
KJE-8316 Radiopharmaceutical Chemistry (10 ECTS, tilbys ved Institutt for kjemi, Doktorgrad)
Ansvarlig for Nevroanatomy, Nevrofysiologi, Nevropsykofarmakologi ved:
MED-2501, Mentale Funksjoner I
MED-2521, Mentale Funksjoner II
FARM-2202 (nå FARM-2206), CNS anatopatofysiologi og psykofarmakologi
Member of research group
CV
CAS i Radiofarmasi, ETH-Zürich (2020)
Sertifisert toksikolog (EUROTOX-registrert toksikolog) (2013)
PhD i veterinærmedisin (nevrotoksikologi og analytisk organisk kjemi) (2011)
MSc i nevrovitenskap og atferdsbiologi (2013)
MSc i kjemi (2003)